منابع مشابه
Deep and wide digging for binding motifs in ChIP-Seq data
SUMMARY ChIP-Seq data are a new challenge for motif discovery. Such a data typically consists of thousands of DNA segments with base-specific coverage values. We present a new version of our DNA motif discovery software ChIPMunk adapted for ChIP-Seq data. ChIPMunk is an iterative algorithm that combines greedy optimization with bootstrapping and uses coverage profiles as motif positional prefer...
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A basic task in the analysis of count data from RNA-seq is the detection of differentially expressed genes. The count data are presented as a table which reports, for each sample, the number of sequence fragments that have been assigned to each gene. Analogous data also arise for other assay types, including comparative ChIP-Seq, HiC, shRNA screening, mass spectrometry. An important analysis qu...
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ژورنال
عنوان ژورنال: Nature Reviews Genetics
سال: 2008
ISSN: 1471-0056,1471-0064
DOI: 10.1038/nrg2423